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PC12 cells in the A+ NAM group presented the highest degree of senescence and apoptosis following NAM treatment ( In another study, in vitro model with primary porcine brain capillary endothelial cells (pBCEC) and 3xTg AD mice

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Alcohol also increases TGF-1 expression while inhibiting granulocyte/macrophage colony-stimulating factor (GM-CSF) in the alveolar space, both of which have been implicated in disrupting and increasing the permeability of the alveolar epithelium (77, 110, 111)

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Modulation of dorsolateral prefrontal cortex functional connectivity after intermittent theta-burst stimulation in depression: Combining findings from fNIRS and fMRI